Muck and Mystery
   Loitering With Intent
blog - at - crumbtrail.org
November 01, 2009
Flame Out

New detail about the benefits of omega-3.

the body converts DHA into Resolvin D2 . . .

The research also suggests that Resolvin D2 could be the basis for a new treatment for diseases including sepsis, stroke and arthritis. Unlike other anti-inflammatory drugs, this chemical does not seem to suppress the immune system. . .

We've also looked in detail at this chemical, determining at least some of the ways it relieves inflammation. It seems to be a very powerful chemical and a small amount can have a large effect. . .

Arthritis, and many other diseases, are caused by inflammation. This means that the body's natural defences against infections are mistakenly directed at healthy tissue.

Previous research has shown that a crucial step in this process occurs when white blood cells, called leukocytes, stick to the inner lining of the blood vessels, called the endothelium.

Researchers studied these blood cells and how they interact with the endothelium in the lab. When they added Resolvin D2 they found that the endothelial cells produced small amounts of nitric oxide, which acts as a chemical signal discouraging the white blood cells from sticking to the endothelial cells and preventing inflammation.

The benefit of DHA isn't news, but the mechanisms aren't well understood. It may be that Resolvin D2 can be synthesized and used as therapy, but it makes the intake of dietary DHA on a regular basis seem sensible too.
Posted by back40 at 01:40 AM | Health

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